East, Alexandra: search on Z-Library

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1

RNA-programmed genome editing in human cells

Jinek, Martin, East, Alexandra, Cheng, Aaron, Lin, Steven, Ma, Enbo, Doudna, Jennifer

Journal:

Year:

2013

Language:

english

File:

PDF, 298 KB

english, 2013

2

Programmable RNA recognition and cleavage by CRISPR/Cas9

O’Connell, Mitchell R., Oakes, Benjamin L., Sternberg, Samuel H., East-Seletsky, Alexandra, Kaplan, Matias, Doudna, Jennifer A.

Journal:

Year:

2014

Language:

english

File:

PDF, 4.93 MB

english, 2014

3

GATA3 Mediates a Fast, Irreversible Commitment to BMP4-Driven Differentiation in Human Embryonic Stem Cells

Gunne-Braden, Alexandra, Sullivan, Adrienne, Gharibi, Borzo, Sheriff, Rahuman S.M., Maity, Alok, Wang, Yi-Fang, Edwards, Amelia, Jiang, Ming, Howell, Michael, Goldstone, Robert, Wollman, Roy, East, Ph

Journal:

Year:

2020

File:

PDF, 7.33 MB

2020

4

RNA Binding and HEPN-Nuclease Activation Are Decoupled in CRISPR-Cas13a

Tambe, Akshay, East-Seletsky, Alexandra, Knott, Gavin J., Doudna, Jennifer A., O’Connell, Mitchell R.

Journal:

Year:

2018

Language:

english

File:

PDF, 3.10 MB

english, 2018

5

Neuropsychological Profile of Children, Adolescents and Adults Experiencing Maltreatment: A Meta-analysis

Masson, Marjolaine, Bussières, Eve-Line, East-Richard, Caroline, R-Mercier, Alexandra, Cellard, Caroline

Journal:

The Clinical Neuropsychologist

Year:

2015

Language:

english

File:

PDF, 283 KB

english, 2015

6

Structural Basis of Pullulanase Membrane Binding and Secretion Revealed by X-Ray Crystallography, Molecular Dynamics and Biochemical Analysis

East, Alexandra, Mechaly, Ariel E., Huysmans, Gerard H.M., Bernarde, Cédric, Tello-Manigne, Diana, Nadeau, Nathalie, Pugsley, Anthony P., Buschiazzo, Alejandro, Alzari, Pedro M., Bond, Peter J., Franc

Journal:

Year:

2015

Language:

english

File:

PDF, 5.51 MB

english, 2015

7

Guide-bound structures of an RNA-targeting A-cleaving CRISPR–Cas13a enzyme

Knott, Gavin J, East-Seletsky, Alexandra, Cofsky, Joshua C, Holton, James M, Charles, Emeric, O'Connell, Mitchell R, Doudna, Jennifer A

Journal:

Nature Structural and Molecular Biology

Year:

2017

Language:

english

File:

PDF, 3.56 MB

english, 2017

8

Efficient Characterization of Protein Cavities within Molecular Simulation Trajectories: trj_cavity

Paramo, Teresa, East, Alexandra, Garzón, Diana, Ulmschneider, Martin B., Bond, Peter J.

Journal:

Journal of Chemical Theory and Computation

Year:

2014

Language:

english

File:

PDF, 9.05 MB

english, 2014

9

Synthesis and structure–activity relationships of tyrosine-based inhibitors of autotaxin (ATX)

James E. East, Andrew J. Kennedy, Jose L. Tomsig, Alexandra R. De Leon, Kevin R. Lynch, Timothy L. Macdonald

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 844 KB

english, 2010

10

The discovery of AZD5597, a potent imidazole pyrimidine amide CDK inhibitor suitable for intravenous dosing

Clifford D. Jones, David M. Andrews, Andrew J. Barker, Kevin Blades, Paula Daunt, Simon East, Catherine Geh, Mark A. Graham, Keith M. Johnson, Sarah A. Loddick, Heather M. McFarland, Alexandra McGrego

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 253 KB

english, 2008

11

Detection of Viral, Bacterial, and Parasitological RNA or DNA of Nine Intestinal Pathogens in Fecal Samples Archived as Part of the English Infectious Intestinal Disease Study

Amar, Corinne Francoise Laurence, East, Claire Louise, Grant, Kathleen A, Gray, Jim, Iturriza-Gomara, Miren, Maclure, Elisabeth Alexandra, McLauchlin, Jim

Journal:

Diagnostic Molecular Pathology

Year:

2005

Language:

english

File:

PDF, 100 KB

english, 2005

12

ATAC-see reveals the accessible genome by transposase-mediated imaging and sequencing

Chen, Xingqi, Shen, Ying, Draper, Will, Buenrostro, Jason D, Litzenburger, Ulrike, Cho, Seung Woo, Satpathy, Ansuman T, Carter, Ava C, Ghosh, Rajarshi P, East-Seletsky, Alexandra, Doudna, Jennifer A,

Journal:

Year:

2016

Language:

english

File:

PDF, 5.91 MB

english, 2016

13

Acne keloidalis nuchae: risk factors and associated disorders - a retrospective study

East-Innis, Althea D. C., Stylianou, Kaderina, Paolino, Alexandra, Ho, Jonathan D.

Journal:

International Journal of Dermatology

Year:

2017

Language:

english

File:

PDF, 79 KB

english, 2017

14

Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies

Cowley, Glenn S, Weir, Barbara A, Vazquez, Francisca, Tamayo, Pablo, Scott, Justine A, Rusin, Scott, East-Seletsky, Alexandra, Ali, Levi D, Gerath, William FJ, Pantel, Sarah E, Lizotte, Patrick H, Jia

Journal:

Scientific Data

Year:

2014

Language:

english

File:

PDF, 668 KB

english, 2014

15

M63. TRANSDIAGNOSTIC NEUROCOGNITIVE DEFICITS IN PSYCHIATRY: A REVIEW OF META-ANALYSES

East-Richard, Caroline, R-Mercier, Alexandra, Nadeau, Danielle, Cellard, Caroline

Journal:

Schizophrenia Bulletin

Year:

2020

File:

PDF, 80 KB

2020

16

Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies

Cowley, Glenn S, Weir, Barbara A, Vazquez, Francisca, Tamayo, Pablo, Scott, Justine A, Rusin, Scott, East-Seletsky, Alexandra, Ali, Levi D, Gerath, William F.J, Pantel, Sarah E, Lizotte, Patrick H, Ji

Journal:

Scientific Data

Year:

2014

Language:

english

File:

PDF, 59 KB

english, 2014

17

Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection

East-Seletsky, Alexandra, O’Connell, Mitchell R., Knight, Spencer C., Burstein, David, Cate, Jamie H. D., Tjian, Robert, Doudna, Jennifer A.

Journal:

Year:

2016

Language:

english

File:

PDF, 5.47 MB

english, 2016

18

RNA Targeting by Functionally Orthogonal Type VI-A CRISPR-Cas Enzymes

East-Seletsky, Alexandra, O’Connell, Mitchell R., Burstein, David, Knott, Gavin J., Doudna, Jennifer A.

Journal:

Year:

2017

Language:

english

File:

PDF, 3.02 MB

english, 2017

19

Identification of a minimal peptide tag for in vivo and in vitro loading of encapsulin

Cassidy-Amstutz, Caleb, Oltrogge, Luke M, Going, Catherine C, Lee, Antony, Teng, Poh K, Quintanilla, David, East-Seletsky, Alexandra, Williams, Evan R, Savage, David F

Journal:

Year:

2016

Language:

english

File:

PDF, 10.05 MB

english, 2016

20

Polar N-terminal Residues Conserved in Type 2 Secretion Pseudopilins Determine Subunit Targeting and Membrane Extraction Steps during Fibre Assembly

Santos-Moreno, Javier, East, Alexandra, Guilvout, Ingrid, Nadeau, Nathalie, Bond, Peter J., Tran Van Nhieu, Guy, Francetic, Olivera

Journal:

Journal of Molecular Biology

Year:

2017

Language:

english

File:

PDF, 2.49 MB

english, 2017

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